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造血細胞移植の分野において画期的な成果が得られるよう日夜努力しています。
●日本白血病研究基金 一般研究賞(2005)
●造血細胞移植の臨床に直接的に応用可能なものである。
●日本小児科学会 ●日本血液学会
●日本小児血液がん学会 ●日本造血細胞移植学会
●American Society for Blood and Marrow Transplantation
●Hirayama M et al. Interleukin-10 spot-forming cells as a novel biomarker of chronic graft-versus-host disease. Haematologica (in press)
●Hirayama M et al. Tolerogenic effect of non-inherited maternal antigens in hematopoietic stem cell transplantation. Frontiers in immunology 3(5):135, 2012
●Hosoki K, Hirayama M, et al. Elevated numbers of cells producing interleukin-5 and interleukin-10 in a boy with kimura disease. Int Arch Allergy and Immunol 158 (suppl 1):70-74, 2012
●Hirayama M et al. Increased level of IFN-γ and IL-4 spot-forming cells on ELISPOT assay as biomarker for acute graft-versus-host disease and concurrent infections. Cells 1(2):61-73,2012
●Iwamoto S, Kumamoto T, Azuma E, Hirayama M, et al. The effect of azithromycin on the maturation and function of murine bone marrow-derived dendritic cells. Clin Exp Immunol 166: 385-92, 2011
●Hirayama M, Azuma E. Major and minor histocompatibility antigens to NIMA: Prediction of a tolerogenic NIMA effect. Chimerism 2: 23-24, 2011
●Araki M, Hirayama M,et al. Prediction of reactivity to non-inherited maternal antigen in MHC-mismatched, minor histocompatibility antigen-matched stem cell transplantation in a mouse model. J Immunol 185: 7739-45, 2010
●Tomizawa D, Koh K, Hirayama M,et al. Outcome of recurrent or refractory acute lymphoblastic leukemia in infants with MLL gene rearrangements: A report from the Japan Infant Leukemia Study Group. Pediatr Blood Cancer 52: 808-13, 2009
●Miyahara M, Hirayama M, et al. Too young to talk of vertigo? Lancet 373: 516, 2009
●Hirayama M, Azuma E, Komada Y. Major and minor histocompatibility antigens to non-inherited maternal antigens (NIMA). Histocompatibility, Chapter 9: 145-162, May, 2012. ISBN 978-953-51-0589-3
●Hirayama M, Azuma E, Komada Y. A biomarker for discrimination of acute graft-versus-host disease from systemic infections: Response to paper by Levine JE et al. in 2012. [e-Letter], Blood June 7, 2012.
●Hirayama M, Azuma E, Komada Y. Successful treatment by donor lymphocyte infusion for severe norovirus infection after allogeneic bone marrow transplantation: Response to paper by Schwartz S et al. in 2011. [e-Letter], Blood, July 27, 2011